Solubility enhancement in pharmaceutical oral solid dosage forms

Three Key Trends in the Solubility Enhancement Industry

With approximately 90% of the active pharmaceutical ingredients that are under development falling into the two low solubility classes of the Biopharmaceutical Classification System (BCS), solubility enhancement technologies represent a strongly growing need for the pharmaceutical industry globally. Our current research covering solubility enhancement technologies and the related excipients market forecasts a compound annual growth rate (CAGR) of over 10% in the period from 2014 to 2024 for this highly important segment, driven by the demand for solubility enhancement excipients. Many solubilization techniques currently co-exist, and even if some can be considered as preferred routes, formulators are still deciding on the technology to use on a case-by-case analysis when developing drugs. Nevertheless, some technologies, such as lipid solubilization, are expected to witness increased acceptance in the United States and Europe, already accounting for more than half of the current global solubility enhancement excipients market value. Due to the relative immaturity of the market, the industry is going through a transitional stage, with many changes affecting not just new market entrants, but also historical market leaders. The competitive landscape is constantly reshaping, and future technology choices on potential blockbusters may bring significant additional changes. Currently, the market for solubility enhancement excipients is dominated by its top five suppliers; however, there is a relatively large number of advanced technology and excipient suppliers that could potentially grow in importance in the short term. Understanding these drivers and many others affecting the solubility enhancement market is key for suppliers of excipients to best position their business in order to leverage the promising growth of what today is a niche market, but will become a key segment of the pharmaceutical excipients industry. To learn more about key market trends in the solubility enhancement industry, please contact our team.

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