Tags: pharmaceuticals

Specialty Excipients for Oral Solid-Dosage-Form Pharmaceuticals: Global Market Analysis and Opportunities

Specialty Excipients for Oral Solid-Dosage-Form Pharmaceuticals: Global Market Analysis and Opportunities

Base Year: 2021
Published: Q4 2022
Regional Coverage: Europe, United States, India, China, Japan, Middle East and Africa, Southeast Asia, Mexico, Rest of the World

This report is a comprehensive analysis examining the Specialty Excipients for Oral Solid Dosage Forms globally, providing details in the functional category segments in each regional market. The reports focus on key trends, developments, changes, challenges, and business opportunities.

Scope

 

  • Pharmaceutical trends influenced by COVID-19 and their impact on the excipients market
  • Consumption in volume and value for each of the excipients considered in the functional categories:
    • — Specialty binders and fillers
    • — Disintegrants
    • — Lubricants
    • — Matrix formers
    • — Coatings
  • Split by country markets
  • Split by suppliers
  • Grades and prices for each excipient
  • Drivers and restraints for each excipient
  • Forecast consumption of each excipients to 2026

Table of Contents

Introduction

Pharmaceutical Industry and Regulatory Overview

  • Regional market for pharmaceutical products
  • Impact of COVID-19
  • Technology trends
  • Regulatory overview

Excipient Categories

  • Binders and fillers
  • Disintegrants
  • Lubricants
  • Coatings
  • Matrix formers

Coverage on each excipient product

  • Introduction
  • Estimated consumption
  • Direct compression vs. wet granulation
  • Industry structure
  • Competitive landscape
  • Impact of COVID-19
  • Appraisal and outlook

INTERACTIVE DATABASE

EXCIPIENT SCOPE

CATEGORY CHEMICAL GROUP
 CHEMISTRY
Binders and Fillers Alginates
Cellulosics Carboxymethylcellulose (CMC)
Ethylcellulose (EC)
Hydroxypropyl cellulose (HPC)
Hydroxypropyl methylcellulose (HPMC)
Methylcellulose (MC)
Microcrystalline cellulose (MCC)
Calcium phosphate (CP)
Directly compressible sucrose
Lactose Monohydrate
Anhydrous
Polyols Mannitol
Sorbitol
Maltitol
Erythritol
Isomalt
Povidone Povidone
Copovidone
Starches Native
Pre-gelatinized/modified starch
Xanthan gum
Disintegrants - Crospovidone
Croscarmellose sodium (CCS)
Sodium starch glycolate (SSG)
Lubricant Stearate Magnesium Stearate
Fumerate Sodium Stearyl Fumerate
Coatings Polymers Polymethacrylates
Cellulosics Hydroxypropyl methylcellulose (HPMC)
Cellulose Acetate Phthalate
Ethylcellulose (EC)
Mannitol
Sorbitol
Formulated Coatings: Instant Release
Formulated Coatings: Controlled Release
Matrix Formers Cellulosics HPMC
CMC
EC
MC
HPC
Alginates
Xanthan gum

Report Benefits

This report serves as an excellent resource for manufacturers and suppliers of different pharmaceutical excipients within key functional categories. Specifically, this report assists subscribers by providing:

  • A highly reliable and independent assessment of the excipients market in oral-solid-dosage-form pharmaceuticals
  • A strong analysis of competitive landscape at the excipient level in the different country markets
  • Key factors in formulation technologies shaping the market for each excipient in the forecast period

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Specialty Excipients for Parenteral Pharmaceuticals: Market Analysis and Opportunities

Specialty Excipients for Parenteral Pharmaceuticals: Market Analysis and Opportunities


Regional Coverage: Europe, United States, India, China, Japan

Base Year: 2020
Published: February 2021
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Base Year: 2022
Published: Q3 2023
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The study is a comprehensive analysis that examines specialty excipients for parenteral pharmaceuticals in three key regional markets, providing details on the functional category segments. It focuses on key trends, developments, challenges, and opportunities.

Scope

  • Consumption in volume and value for excipients in parenteral pharmaceuticals, including:​
    • — Lyophilization​
    • — Liquid solution​
    • — Suspensions​
  • Excipient products​
  • Grades and prices​
  • Competitive landscape​
  • Drivers and restraints ​
  • Outlook and forecast to 2027

Product Scope

Introduction ​

Pharmaceutical Industry and Regulatory Overview​

Parenteral Formulations​

  • Liquid solutions​
  • Lyophilization​
  • Suspensions​

For each formulation type:

  • Formulation examples​
  • Excipients​
  • Consumption​
  • Outlook and appraisal ​

Parenteral Excipients​

  • Introduction​
  • Market volume and value​
  • Grades and prices​
  • Supplier sales​
  • Outlook and appraisal​

REPORTS & DATABASE

This consists of a concise report per country/region and a fully interactive database. While the dataset allows users to customize views according to supplier, excipient category, and excipient, the reports provide subscribers with enlightening explanations on database figures, forecasts models, and market drivers.

FUNCTION​ EXCIPIENT PRODUCT​​
Bulking agents and lyoprotectants​​​ ​Mannitol​​
​​​​​ Sucrose​​​​​​
​​​​​ Trehalose​​​​​​
​​​​​ PEG​​​​​​​
​​​​​ Povidone
​​​​​Tonicity adjusting agents​ Dextrose​​​​​​​
​​​​​ Glycerin​​​​​​​
​​​​​ Mannitol​​​​​​​
​​​​​ Sodium chloride​​​​​​​
​​​​​Solubilizing agents​ Propylene glycol​​​​​​​
​​​​​ Glycerin​​​​​​​
​​​​​ Polyethylene glycol​​​​​​​
​​​​​ Sorbitol​​​​​​​
​​​​​ Dimethylacetamide​​​​​​​​
​​​​​ Castor oil
​​​​​Complexing and dispersing agents​ Cyclodextrins​​​​​​​​
Flocculating/suspending agents​​​​​​ Carboxymethyl cellulose​​​​​​​​
​​​​​ Gelatin​​​​​​​​
​​​​​ Methyl cellulose​​​​​​​​
​​​​​ Povidone​​​​​​​​
​​​​​Wetting agents​ Glycerin​​​​​​​​
​​​​​ Ethanol
​​​​​ Propylene glycol​​​​​​​​​
​​​​​Surfactants (wetting agents)​ Lecithin​​​​​​​​​
​​​​​ Polysorbate 20​​​​​​​​​
​​​​​ Polysorbate 80​​​​​​​​​
​​​​​ Poloxamer​​​​​​​​​​
​​​​​Solvent system​ Ethanol​​​​​​​​​​
​​​​​ Glycerin​​​​​​​​​​
​​​​​ Castor oil​​​​​​​​​​
​​​​​ Propylene glycol​​​​​​​​​​ (PG)

Report Benefits

This report serves as an excellent resource for manufacturers and suppliers of specialty excipients. Specifically, it assists subscribers by providing:

  • A highly reliable and independent assessment of excipients in parenteral pharmaceuticals in the three key regional markets
  • An analysis of application in different formulation types and competitive landscape
  • An appraisal of market trends and supply and demand drivers, plus a forecast

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Solubility Enhancement in Pharmaceutical Oral Solid and Parenteral Dosage Forms

Solubility Enhancement in Pharmaceutical Oral Solid and Parenteral Dosage Forms

Base Year: 2020
To be published: Q3 2021
Regional Coverage: Global

A comprehensive analysis examining the market for Solubility Enhancement in Pharmaceutical Oral Solid and Parenteral Dosage Forms globally.

The reports will focus on key trends, developments, changes, challenges, and business opportunities.

Scope

  • Consumption of solubility enhancement excipients in OSDF and parenteral dosage forms
  • Consumption of excipients by technology and methods used
  • Competitive landscape for the excipients for solubility enhancement
  • Technology and process analysis for solubility enhancement techniques
  • Detailed analysis of key drivers and restraints of the excipients consumption for solubility enhancement
  • Consumption forecast of excipients to 2030

Table of Contents

Introduction 

Executive Summary

An overview of the report findings plus forecast based on Kline’s Future View Forecasting Model

Introduction to Solubility Enhancement

  • Global pharmaceutical industry: overview
  • Regulatory scenario
  • Current situation of poorly bioavailable active

Solubility Enhancement Technologies

  • Overview of the technologies
  • Role of SE technologies in the oral solid and parenteral dosage forms
  • Advantages, disadvantages, and comparative assesment of the technologies
  • Commercial examples of technologies in the solubility enhancement market
  • Excipients used in the technologies
  • Upcoming technologies
  • Outlook

Comparative Assesment of SE technologies by dosage forms (OSDF versus parenteral)

  • Current situation and outlook

Solubility Enhancement Excipients

  • Introduction
  • Grades and prices
  • Consumption of excipient in the oral solid and parenteral dosage forms
  • Competitive Landscape
  • Commercial examples of drugs using excipient in solubility enhancement market
  • Novel/upcoming excipients for solubility enhancement
  • Outlook

Competitive Landscape

  • Introduction
  • Industry Structure
  • Supplier market share in the oral solid and parenteral dosage forms
  • Competitive Landscape
  • Short Profiles on major suppliers
  • Major drug delivery companies
  • Major customers

Comparative Assessment of SE excipients by dosage forms (OSDF versus parenteral)

  • Current consumption and outlook

Appraisal and Outlook

  • Major trends in oral solid parenteral dosage forms
  • Drivers and Restraints in solubility enhancement market
  • Outlook and forecast for the solubility enhancement market
Product Scope
Excipient Category Excipient type
Surfactants Cremophors
Polyethylene Glycols (PEG)

Polysorbates

Poloxamers

Solutol HS 15

Polyoxyl stearates

N-methyl-2-pyrrolidone

Ethanol

Glycerin

Lecithin

Docusate sodium (DSS)

Sodium lauryl sulfate (SLS)
Polymers Copovidone

HPMC

Polymethacrylates (PMAs)

HPMCAS

Povidone (PVP)

HPC

Polyvinyl

Caprolactam-polyvinyl acetate-polyethylene glycol copolymer

PEO

HPMCP
Lipid-based excipients (including water-insoluble surfactants)
Cyclodetrins
Mesoporous Silica
Dendrimers
Technology Scope
Technology Process
Particle

size reduction

 Micronization
Nanonization
Lipid Solubilization Several
Modification

of crystal habit

 Polymorphs
Pseudopolymorphs
Soild Dispersions Spray drying process
Hot-melt extrusion process
Complexation Complexation with cyclodextrins
Cryogenic techniques Lyophilization
Use of Liposomes and proliposomes
pH adjustment
Salt formation
Cosolvency
Hydrotopy
Coprocessed excipients
Use of Ion exchange resins
Solid Lipid Nanoparticles
Liquisolid Technology
Use of Silica
Use of Dendrimers

Report Benefits

This study will assist suppliers of pharmaceutical excipients in identifying opportunities within the global market of solubility enhancement. It will also serve as an invaluable tool in the strategic planning process:

  • Develop business strategies by understanding the trends and developments that are driving the global solubility enhancement excipients market
  • Identification of key growth areas by excipient type, application dosage form, and technologies of their use to enable development of targeted sales and marketing strategies
  • Forecasting scenarios from which to base solid strategic business plans
  • Competitive intelligence for use in benchmarking

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Excipients for Topical Pharmaceuticals: Market Analysis and Opportunities

Excipients for Topical Pharmaceuticals: Market Analysis and Opportunities

Excipients for Topical Pharmaceuticals: Market Analysis and Opportunities


Regional Coverage: United States, Europe, India

Base Year: 2018
Published August 2019
Forecasts to 2023
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Base Year: 2022
To be Published: Q4 2023
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The study is a comprehensive analysis on the market of excipients in topical pharmaceuticals in the biggest regional markets. It extensively covers a variety of excipient categories and provides a deep dive into individual excipient markets, facilitating the understanding of market trends and the identification of market opportunities.

Report Content and Scope

Introduction

Topical Drugs Industry and Regulatory Overview

Each category chapter to contain:

  • Introduction
  • Excipient products
  • Consumption
  • Prices
  • Industry structure
  • Competitive landscape
  • Appraisal and outlook

Categories Covered:

  • Antimicrobials
  • Antioxidants
  • Emollients
  • Emulsifiers and surfactants
  • Rheology control agents
  • Silicones
  • Solubilizers and film formers

INTERACTIVE DATABASE

Product Scope

EXCIPIENT CATEGORY EXCIPIENT GROUP EXCIPIENT
Emulsifiers Ethoxylates Alcohol ethoxylates
Fatty esters Glyceryl Stearates
Sorbitan Esters
Polysorbates
Alkyl esters Isopropyl Stearate/Palmitate
Synthetic organic polymers PEG Derivatives
(PEG-Stearates, PEG lauryl ether, etc.)
Alkyl esters Isopropyl Stearate/Palmitate
Synthetic organic polymers PEG Derivatives
(PEG-Stearates, PEG lauryl ether, etc.)
Glucolipids Cetearyl alcohol/glucoside
Poloxamers
Glucolipids Stearyl alcohol
Cetearyl alcohol
Cetyl alcohol
Glucoside
Anionic emulsifiers Stearyl Sulfates
Sodium Lauryl Sulfate
Cetyl Sulfates
Lipid-based
Rheology control agents Cellulose polymers and glucose derivatives HPMC
HEC
CMC
Others
Synthetic organic polymers Carbomer
Acrylate copolymers
Cationic LDP
Anionic LDP
Natural gums Xanthan
Carrageenan
Sodium alginate
Modified starch
Inorganics Silica (hydrophilic and hydrophobic)
Antimicrobials Preservatives Phenoxyethanol
Parabens
Benzoic acid and benzoates
Sorbic acid and sorbates
Benzalkonium chloride
Others
Antioxidants Antioxidants Butylated hydroxyanisole
Butylated hydroxytoluene
Emollients Polyol Sorbitol
Emollient esters Isopropyl palmitate
Classic
Complex
Natural oils Castor oil
Lanolin/derivatives
Squalane
Others
Waxes Carnauba wax, Cetyl ester wax,
Emulsifying wax, Microcrystalline wax,
Paraffin wax, White wax, Yellow wax
Synthetic organic polymers Polyethylene glycol (PEG)
Petrolatum
Silicones Silicones Dimethicones
Cyclomethicones
PEG/PPG dimethicones
Solubilizers and film formers Povidone
Copovidone

Report Benefits

This report serves as an excellent resource for manufacturers and marketers of specialty excipients to the formulators of topical pharmaceuticals. Specifically, this report assists subscribers by providing:

  • A highly reliable and independent assessment of the market of excipients in each category and role
  • Deep understanding of trends in the industry related to consumers, technology, and products
  • An insightful analysis on market outlook and forecast to each excipient level

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Excipients for Nutraceutical Oral Solid Dosage Forms: Market Analysis and Opportunities

Excipients for Nutraceutical Oral Solid Dosage Forms: Market Analysis and Opportunities

Excipients for Nutraceutical Oral Solid Dosage Forms: Market Analysis and Opportunities


Regional Coverage: United States, Europe

Base Year: 2019
Published 1st Quarter 2020
Forecasts to 2024
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Base Year: 2022
Published: Q3 2023
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This study is a comprehensive analysis on the market of excipients in nutraceutical oral solid doses in the two biggest regional markets. It extensively covers a variety of excipient categories and provides a deep dive into individual excipient markets, facilitating the understanding of market trends and the identification of market opportunities.

Report Content and Scope

Introduction

Nutraceuticals Industry and Regulatory Overview

Each category chapter to contain:

  • Introduction
  • Excipient products
  • Consumption
  • Dosage forms
  • Prices
  • Industry structure
  • Competitive landscape
  • Appraisal and outlook

Categories Covered:

  • Binders and fillers
  • Disintegrants
  • Matrix formers
  • Coatings
  • Lubricants and lipids
  • Bioavailability enhancers

INTERACTIVE DATABASE

Product Scope

EXCIPIENT CATEGORY EXCIPIENT GROUP EXCIPIENT
Binders and Fillers Cellulosics MCC
HPMC
EC
HPC
CMC
L-HPC
Povidone Povidone
Copovidone
Lactose Monohydrate
Anhydrous
Starch Native
Pre-gelatinized/modified
Polyols Sorbitol
Mannitol
Erythritol
Isomalt
Maltitol
Directly compressible sucrose
Gelatin
Coprocessed
Minerals Calcium phosphate
Calcium carbonate
Calcium hydroxide
Calcium oxide
Calcium sulfate
Calcium silicate
Silicon dioxide/precipitated silica
Titanium dioxide
Sodium alginate
Talc
Magnesium carbonate
Potassium chloride
Disintegrants CCS
Crospovidone
SSG
Matrix formers Cellulosics HPMC
CMC
Coatings Cellulosics HPMC
EC
Other cellulosics (split out)
Polymers Starch
Polymethacrylates
Povidone
Formulated Coatings
Lubricants and Lipids Magnesium stearate
Glycerides Hydrogenated vegetable oil
Medium-chain triglycerides
Bioavailability Enhancers Cyclodextrins
Colloidal silica
Glycerides

Report Benefits

This report serves as an excellent resource for manufacturers and marketers of specialty excipients to the formulators of nutraceutical oral solid doses. Specifically, this report assists subscribers by providing:

  • A highly reliable and independent assessment of the market of excipients in each category and role
  • Deep understanding of trends in the industry related to consumers, technology, and products
  • An insightful analysis on market outlook and forecast to each excipient level

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Active Ingredients in Nutraceuticals: Market Analysis and Opportunities

Active Ingredients in Nutraceuticals: Market Analysis and Opportunities

Base Year: 2019
Published: December 2020
Regional Coverage: Europe, United States

A comprehensive analysis examining the active ingredients in nutraceuticals in the two key regional markets, providing details in the functional category segments. The report will focus on key trends, developments, challenges, and opportunities.

Scope

  • Consumption in volume and value for actives in nutraceuticals considered in the functional categories:
    • Carotenoids
    • Enzymes
    • Polyphenols and flavonoids
    • Prebiotics
    • Probiotics
    • Proteins and peptides
    • Vitamins and minerals (only synthetic active ingredients)
  • Market split by supplier
  • Grades and prices
  • Drivers and restraints
  • Outlook and forecast to 2024

Table of Contents

Introduction

Executive Summary

Nutraceutical Market Overview

An overview of the market of finished
nutraceutical products

Market Sizing

  • Volume and value
  • Key products

Grades and Prices

  • Key products

Market Analysis by Health Benefit

  • Bone health improvement
  • Cardiovascular health (blood pressure control, blood clots, cholesterol controls, etc.)
  • Diabetes control
  • Eye health improvement/eye disease control
  • Immunity boosters
  • Mental health
  • Metabolic system support
  • Skin health
  • Tumor control

Supplier Share Analysis

Outlook and Forecast

Report Benefits

This report serves as an excellent resource for manufacturers and suppliers of nutraceutical active ingredients. Specifically, it assists subscribers by providing:

  • A highly reliable and independent assessment of the nutraceutical actives market in the two key regional markets
  • An appraisal of market trends and supply and demand drivers
  • Identification of key growth areas in functional product categories

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Biologics 2023 thumbnail

Biologics: Market Opportunities for Chemical Suppliers

Biologics: Market Opportunities for Chemical Suppliers


Regional Coverage: Global

Base Year: 2020
Published: Q3 2021
Forecasts to 2025
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Base Year: 2023
To be Published: Q1 2024
Forecasts to 2028
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The influx of biologics in the drug development pipeline is creating new opportunities for various chemical products along the entire value chain. The opportunities lie for not only chemicals used as key components of finished biologic drug dosage but also the ingredients that play an important role in the development and manufacturing of the drug itself. With this study, Kline provides a comprehensive assessment of opportunities created by biologics for chemicals suppliers.

Scope

  • A comprehensive analysis of global biopharmaceuticals industry developments and their impact on demand for specialty chemicals in different stages of production, including:
    • — Upstream manufacturing
      • — Classic cell culture media, cell expression systems, cell culture ingredients and supplements, and buffers
    • — Downstream processing
      • — Stabilizers, surfactants, salts, antioxidants, and buffers
    • — Final formulation
      • — Stabilizers and bulking agents, surfactants, salts, antioxidants, buffers, vaccine adjuvants, and chelating agents

Table of Contents

Introduction to the Biopharmaceutical Industry

  • Overview of biologic pharmaceuticals
  • Types of biologic pharmaceuticals
  • Major biopharmaceutical companies
  • Commercial examples of biologic formulations

Bioprocessing Techniques

  • Overview
  • Trends and outlook

Recent Developments in the Biopharmaceutical Industry

  • Pandemic-caused dynamics
  • Developments in the drug pipeline
  • Ingredient consumption patterns
  • Existing and future drug options

Ingredients for Bioprocessing

  • Market size
  • Grades and prices
  • Supplier landscape
  • Potential growth scenarios
  • Biologics ingredients and excipients forecast

Report Benefits

 

This report helps chemical suppliers understand the entire biologics value chain and identify business opportunities within a key growth area. It also serves as an invaluable tool in the strategic planning process. In addition, the report allows subscribers to:

  • Develop business strategies by understanding the trends that are driving the consumption of chemicals related to biopharmaceutical processing and formulation globally
  • Identify key market participants at various levels of the value chain
  • Develop market-entry and market-expansion strategies and identify specific chemicals or categories poised for strong growth

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