Solubility Enhancement in Pharmaceutical Oral Solid and Parenteral Dosage Forms

Base Year: 2020
To be published: Q3 2021
Regional Coverage: Global

A comprehensive analysis examining the market for Solubility Enhancement in Pharmaceutical Oral Solid and Parenteral Dosage Forms globally.

The reports will focus on key trends, developments, changes, challenges, and business opportunities.


  • Consumption of solubility enhancement excipients in OSDF and parenteral dosage forms
  • Consumption of excipients by technology and methods used
  • Competitive landscape for the excipients for solubility enhancement
  • Technology and process analysis for solubility enhancement techniques
  • Detailed analysis of key drivers and restraints of the excipients consumption for solubility enhancement
  • Consumption forecast of excipients to 2030

Table of Contents


Executive Summary

An overview of the report findings plus forecast based on Kline’s Future View Forecasting Model

Introduction to Solubility Enhancement

  • Global pharmaceutical industry: overview
  • Regulatory scenario
  • Current situation of poorly bioavailable active

Solubility Enhancement Technologies

  • Overview of the technologies
  • Role of SE technologies in the oral solid and parenteral dosage forms
  • Advantages, disadvantages, and comparative assesment of the technologies
  • Commercial examples of technologies in the solubility enhancement market
  • Excipients used in the technologies
  • Upcoming technologies
  • Outlook

Comparative Assesment of SE technologies by dosage forms (OSDF versus parenteral)

  • Current situation and outlook

Solubility Enhancement Excipients

  • Introduction
  • Grades and prices
  • Consumption of excipient in the oral solid and parenteral dosage forms
  • Competitive Landscape
  • Commercial examples of drugs using excipient in solubility enhancement market
  • Novel/upcoming excipients for solubility enhancement
  • Outlook

Competitive Landscape

  • Introduction
  • Industry Structure
  • Supplier market share in the oral solid and parenteral dosage forms
  • Competitive Landscape
  • Short Profiles on major suppliers
  • Major drug delivery companies
  • Major customers

Comparative Assessment of SE excipients by dosage forms (OSDF versus parenteral)

  • Current consumption and outlook

Appraisal and Outlook

  • Major trends in oral solid parenteral dosage forms
  • Drivers and Restraints in solubility enhancement market
  • Outlook and forecast for the solubility enhancement market
Product Scope
Excipient Category Excipient type
Surfactants Cremophors
Polyethylene Glycols (PEG)



Solutol HS 15

Polyoxyl stearates





Docusate sodium (DSS)

Sodium lauryl sulfate (SLS)

Polymers Copovidone


Polymethacrylates (PMAs)


Povidone (PVP)



Caprolactam-polyvinyl acetate-polyethylene glycol copolymer



Lipid-based excipients (including water-insoluble surfactants)
Mesoporous Silica
Technology Scope
Technology Process

size reduction

Lipid Solubilization Several

of crystal habit

Soild Dispersions Spray drying process
Hot-melt extrusion process
Complexation Complexation with cyclodextrins
Cryogenic techniques Lyophilization
Use of Liposomes and proliposomes
pH adjustment
Salt formation
Coprocessed excipients
Use of Ion exchange resins
Solid Lipid Nanoparticles
Liquisolid Technology
Use of Silica
Use of Dendrimers

Report Benefits

This study will assist suppliers of pharmaceutical excipients in identifying opportunities within the global market of solubility enhancement. It will also serve as an invaluable tool in the strategic planning process:

  • Develop business strategies by understanding the trends and developments that are driving the global solubility enhancement excipients market
  • Identification of key growth areas by excipient type, application dosage form, and technologies of their use to enable development of targeted sales and marketing strategies
  • Forecasting scenarios from which to base solid strategic business plans
  • Competitive intelligence for use in benchmarking

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